Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response
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چکیده
منابع مشابه
Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response.
Exposure to arsenic is associated with an increased risk of lung disease. Novel strategies are needed to reduce the adverse health effects associated with arsenic exposure in the lung. Nrf2, a transcription factor that mediates an adaptive cellular defense response, is effective in detoxifying environmental insults and prevents a broad spectrum of diseases induced by environmental exposure to h...
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Sulforaphane (SFN) is a natural and highly effective antioxidant. Studies suggest that SFN protects cells and tissues against cadmium (Cd) toxicity. This study investigated the protective effect of SFN against oxidative damage in the testes of Kunming mice exposed to cadmium, and explored the possible molecular mechanisms involved. Cadmium greatly reduced the serum testosterone levels in mice, ...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2012
ISSN: 0041-008X
DOI: 10.1016/j.taap.2012.08.028